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An abstract image of a brain with speech fibers and brain tumors. © Lucius Fekonja

The Speech Connectome in Brain Tumor Patients

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For whom?

Patients with a suspected brain tumor in a speech relevant area, who are at least 18 years old.


What is done?

Certain areas of the brain are responsible for language processing. Impairment of these areas can occur when a tumor grows in close proximity to them. We assume that certain language functions are associated with damage to specific connections. Using various MRI sequences, we calculate the individual connectivity of the brain and investigate how the tumor affects the connections and language function.


How does it work?

We conduct neuropsychological tests for functional evaluation. Afterwards, we combine these results with the "connectome" - the entirety of brain connections measured through MRI data - in statistical models to make predictions about language function in relation to impairment.


What effort is involved in participating in the study?

The one-hour, additional, and high-quality MRI measurements are carried out once before and once after the surgery.


What advantages does participation in the study offer?

The study aims to initially investigate the relationship between language function and the tumor, which is why we cannot promise you any individual benefits. Our expectation is that through the high-quality MRI data and the precise examination of language function, the impact of the tumor on the cerebral network can be better mapped. By participating, you will be in close contact with the study personnel and can become familiar with the environment of the clinic.


How is participation in the study possible?

If you are interested in participating, please contact your treating neurosurgeon, the surgical management team, or a member of the study team for further information.

Contact Person

Dr. rer. medic. Lucius Fekonja

Research Associate, VisualizationCharité - Universitätsmedizin Berlin

Postal address:Charitéplatz 110117 Berlin

Campus / internal address:Bettenhochhaus, Luisenstr. 64